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Hacking the Brain’s Security System
by Rob Mitchum The brain is a privileged organ, afforded protections denied to all the other organs of the body. Though the circulatory system functions much the same way above and below the neck,...
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Gut bacteria are protected by host during illness
E. Coli and macrophages, courtesy cancer.gov To protect their gut microbes during illness, sick mice produce specialized sugars in the gut that feed their microbiota and maintain a healthy microbial...
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Cancer Research Month: Immunology, Pharmacogenomics and Experimental...
The research conducted by the faculty at the University of Chicago Medicine Comprehensive Cancer Center is organized into six independent, but interactive, Scientific Programs that represent the...
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Cell signal whets appetites for tumor-devouring dendritic cells
Dendritic Cell Revealed In a paper published online Aug. 31 by Nature Medicine, researchers based at the University of Chicago report that using mice with an intact immune system provides a much more...
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Rising star in microbiome research focuses on basics in the lab
Taylor Feehley (left) with Cathryn Nagler, PhD Taylor Feehley just defended her PhD thesis on how gut bacteria interact with the immune system, work that someday could help prevent the development of...
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Obesity linked to inflammation and organ transplant rejection
A transplant surgical team at work at the Center for Care and Discovery at the University of Chicago Medicine. (Photo by Robert Kozloff) One of the reasons obesity is so dangerous for long-term health...
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Microbiota affect the rate of transplant acceptance and rejection
Maria-Luisa Alegre, MD, PhD, (left) with graduate student Kevin Lei. Success rates for transplants of skin, lungs, and intestines—organs that are exposed to the outside world—are much worse than...
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Growing up on an Amish farm protects children against asthma by reprogramming...
Cows in an Amish barn House dust differences between communities affect immune development By probing the differences between two farming communities—the Amish of Indiana and the Hutterites of South...
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Seemingly innocuous virus can trigger celiac disease
Infection with reovirus, a common but otherwise harmless virus, can trigger the immune system response to gluten that leads to celiac disease, according to new research from the University of Chicago...
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$100 million gift establishes Duchossois Family Institute to develop ‘new...
A Chicago-area family with a deep commitment to supporting science and medicine is giving $100 million to establish The Duchossois Family Institute at the University of Chicago Medicine, which seeks...
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What we know about how cells take out the trash could fight viruses too
Mouse cells infected with norovirus. The bigger black dots mark the replication complexes, or compartments the viruses build for themselves to hide from the immune system, and the smaller black dots...
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Gene therapy via skin could treat many diseases, even obesity
A research team based at the University of Chicago has overcome challenges that have limited gene therapy and demonstrated how their novel approach with skin transplantation could enable a wide range...
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Scientists identify gene that controls immune response to chronic viral...
Image: Immunity For nearly 20 years, Tatyana Golovkina, PhD, a microbiologist, geneticist and immunologist at the University of Chicago, has been working on a particularly thorny problem: Why are some...
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